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July 13, 2009 at 8:24 AMComments: 0 Faves: 0

History and Use of Commiphora Mukul for Weight Loss

By Smarty More Blogs by This Author

Commiphora Mukul: Botany

Commiphora mukul, also known as Guggul, is one type of flowering plant within the family Burseraceae, which is native to central Asia, northern Africa, and northern India. It is a fairly tolerant plant, preferring semi arid climates with poor soil. It consists of a small flowering shrub with thorns on its branches. The flowers are particularly small, with four petals of red or pink. The plant itself is contains both male and female parts and is capable of self fertilization.

Commiphora Mukul: Historical Use

Guggul was historically used by the people of India as Ayturvedic medicine. Ayurvedic medicine is the combination of traditional treatment methods for certain conditions. According to Ayurvedic medicinal practice, Guggul was utilized for the conditions of obesity and osteoarthritis. It has been correlated with ability to reduce and manage cholesterol levels and for improvements to the skin, particularly acne.

Commiphora Mukul: Mechanism of Action

The exact molecular mechanisms of Commiphora mukul have yet to be determined with accuracy. However, there are several known theories for this mechanism of action. One such proposal suggests that Guggul is responsible for decreases in production of hepatic steroid. This reduction is responsible for increased catabolism of LDL cholesterol in the blood. Similar to this, it has also been suggested that Guggul increases the number of hepatic binding sites for LDL cholesterol. If cholesterol is utilized by the cells, it is not present in the blood stream. While these mechanisms have been proposed, there is preliminary evidence to support both theories, but no scientific evidence has clearly proven that either mechanism is responsible for the results.

Commiphora Mukul and Weight Loss

Commiphora mukul is a natural substance that may be utilized in conjunction with healthy lifestyle and dietary changes to aid in weight loss. Weight loss has been associated with the ability of Guggul to reduce the overall production of thyroid hormone. The potential for weight loss is associated with Guggul as thyroid hormone is necessary for the proper break down of proteins, carbohydrates, and fats. There is limited scientific evidence to support this capability, but more studies are currently under investigation.

Commiphora Mukul: Dosage

The dosages used in clinical studies have varied greatly, but this is standard. The normal dosage of Guggul for use in the management of hypercholesterolemia and weight loss typically ranges from 75-150 milligrams lasting for a minimum period of one month. However, dosages much greater than this have been utilized. Discuss the use and dosage of Commiphora mukul with your physician.

Commiphora Mukul: Adverse Effects?

There is little evidence to support that Commiphora mukul is associated with adverse side effects. However, dosage should be watched carefully, as there have been little case studies completed to determine overdose levels and effects. While it is uncommon for side effects to be reported, the most common are mild and include nausea, diarrhea, headache, hiccups, and restlessness. As always, it is recommended that you discuss all treatment methods with your physician to avoid any adverse interactions with current medications or side effects.

Sources:

http://www.ncbi.nlm.nih.gov/pubmed/7848901

http://www.jpgmonline.com/article.asp?issn=0022-3859;year=1991;volume=37;issue=3;spage=132;epage=5;aulast=Lata

http://www.puritan.com/vf/healthnotes/hn_live/Herb/Guggul.htm

http://www.medscape.com/viewarticle/505754

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