Arthro-IonX helps to decrease pain and weakness and stimulate healing. You may use Arthro-IonX along with other medications or supplements. It is homeopathic in nature and so it will not negatively interact with other physical substances. In addition, I find it helpful to follow a holistic approach by giving some nutritional supplements to accompany Arthro-IonX. The supplements I recommend are digestive enzymes with meals, MSM, probiotics, vitamin C, and fish oil. Arthro-IonX will help the body to better utilize the nutrition for a synergistic response. In addition, I would avoid giving water that contains chlorine or fluoride. You might also want to try feeding food that is grain free for a while. Another thing I have found helpful is to have a veterinary chiropractor evaluate and make any corrections as necessary. Please let us know how you do or if you have any other questions.