I would start with Promaxol rather than Anxietrex. Promaxol would be a good choice for your dog because it contains the stronger LM potencies. After improvement is seen then you can switch over to Arthro-IonX. It would be helpful to gradually reduce the prednisone under your veterinarian's supervision. It can make the anxiety worse. In addition it is helpful to give Canine Probiotics with each meal, Omega 3,6,9, MSM, and vitamin C daily. (We carry the first two and the other two you can get at a health food store.) The oligotherapeutic mineral base found in the IONX products helps the body to better utilize the other nutritional substances given for a synergistic response and faster healing. Also be sure to give sufficient fresh water that is free of chlorine and fluoride. If you can gradually phase into a grain free diet that can be helpful too. The other thing that is sometimes beneficial is to have a certified veterinary chiropractor check for spinal alignment and make any corrections as necessary. Acupuncture is also helpful for disc disease. Part of the anxiety might be related to the back discomfort. If more help is needed Anxietrex can be given at a different time of the day than when Promaxol is given.
Please let us know how you progress or if you have any other questions.