You may use ARTHRO-IONX along with other medications or supplements. It is homeopathic in nature and so it will not negatively interact with other physical substances. You can use the drugs along with ARTHRO-IONX to provide comfort while healing is occurring. Healing takes more time than just suppressing symptoms. ARTHRO-IONX helps to stimulate healing. In addition I find it helpful to follow a holistic approach by giving some nutritional supplements to accompany ARTHRO-IONX. The supplements I recommend are Canine Probiotics and Omega 3,6,9. ARTHRO-IONX will help the body to better utilize the nutrition for a synergistic response. Please let us know how you progress or if you have any other questions.