Thank you for your patience in getting the information you requested. Canine Probiotics is manufactured in the United States in a NASC (National Animal Supplement Council) facility. This allows for extensive Federal government inspections.
The majority of the ingredients are from the U.S. but not all. The ones from outside the country are:
N-Acetyl Glucosamine -China
FOS (fructooligosaccharides) - Belgium
Ginger (Zingiber officinale) Root Powder - China or Nigeria
Lipase - Italy
Papain - Republic of Congo
The other ingredients are from the U.S.
You need not worry about quality control.